Clone: MEM-258
Specificity: Recognizes the human CD46 cell surface antigen, a broadly expressed glycoprotein also known as membrane co-factor protein (MCP). CD46 functions as an inhibitor of complement activation limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilization.
Antibody Modification: FITC
Presentation: PBS, 0.09% Sodium Azide, 1% BSA
Immunogen: HPB-ALL cell line.
Gene: CD46
Description: CD46 antibody LS-C44290 is an FITC-conjugated mouse monoclonal antibody to human CD46. Validated for Flow.
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 or 100 ul whole blood. Method sheets are available on request.
Synonyms: CD46, AHUS2, CD46 antigen, MCP, Measles virus receptor, TLX, MIC10, TRA2.10, Membrane cofactor protein
Recommended Storage: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Concentration: 0.1 mg/ml
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