CD5 (Mantle Cell Lymphoma Marker)(CD5/2418), CF740 conjugate, 0.1mg/mL

CD5 (Mantle Cell Lymphoma Marker)(CD5/2418), CF740 conjugate, 0.1mg/mL
SKU
BTMBNC742418-100
Packaging Unit
100 uL
Manufacturer
Biotium

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Description: Recognizes a 67 kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e. g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma ( ) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal - Mus musculus (mouse), Bos taurus (bovine)

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Clone: CD5/2418

Immunogen: Recombinant fragment of human CD5 protein (around aa 269-366) (exact sequence is proprietary)

Antibody Reactivity: CD5

Entrez Gene ID: 921

Z-Antibody Applications: Flow (verified)/IF (verified)/IHC, FFPE (verified)

Verified AB Applications: Flow (verified)/IF (verified)/IHC (FFPE) (verified)
More Information
SKU BTMBNC742418-100
Manufacturer Biotium
Manufacturer SKU BNC742418-100
Package Unit 100 uL
Quantity Unit STK
Reactivity Human
Clonality Monoclonal
Application Immunofluorescence, Flow Cytometry, Immunohistochemistry
Isotype IgG2c kappa
Host Mouse
Conjugate Conjugated, CF740
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