CFTR (Cystic Fibrosis Transmembrane Conductance Regulator)(rCFTR/1342), CF740 conjugate, 0.1mg/mL

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator)(rCFTR/1342), CF740 conjugate, 0.1mg/mL
SKU
BTMBNC742291-500
Packaging Unit
500 uL
Manufacturer
Biotium

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Description: Recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3', 5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal - Mus musculus (mouse), Bos taurus (bovine)

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Clone: rCFTR/1342

Immunogen: Recombinant full-length human CFTR protein

Antibody Reactivity: CFTR

Entrez Gene ID: 1080

Z-Antibody Applications: IHC, FFPE (verified)

Verified AB Applications: IHC (FFPE) (verified)
More Information
SKU BTMBNC742291-500
Manufacturer Biotium
Manufacturer SKU BNC742291-500
Package Unit 500 uL
Quantity Unit STK
Reactivity Human, Mouse (Murine)
Clonality Recombinant
Application Immunohistochemistry
Isotype IgG1 kappa
Host Mouse
Conjugate Conjugated, CF740
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