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CAS Number: 586976-24-1
Description: CTPB is a potent activator of p300 activity, but not of PCAF (p300/CBP-associated factor). This compound has been shown to enhance p300 HAT-dependent transcriptional activation from in vitro assembled chromatin template. CTPB has also been noted to be a membrane-impermeable molecule that requires a carrier to move across the membrane barrier of cells.
Format: White to off-white crystalline solid.
Purity: ≥97%
Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Warnings: Protect from light and air.
Biosafety Level: Not applicable (BSL-1)
References: 1. Balasubramanyam, K., et al. 2003. J. Biol. Chem. 278: 19134-19140.
2. Campo, N., et al. 2007. J. Bacteriol. 189: 6021-6027.
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