Cys-MC-GGFG-Dxd, CAS 3025787-83-8

Product Description: Cys-MC-GGFG-Dxd is a conjugate of Cys and Deruxtecan (HY-13631E). Cys-MC-GGFG-Dxd is a linker-toxin building block in antibody-drug conjugates (ADCs) used to link antibody Cys residues to cytotoxic drugs. Cys-MC-GGFG-Dxd can be used in cancer research[1][2].

Applications: Cancer-programmed cell death

Formula: C55H63FN10O15S

References: [1]Peng H. Perspectives on the development of antibody-drug conjugates targeting ROR1 for hematological and solid cancers. Antib Ther. 2021 Oct 15;4(4):222-227./[2]Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.

CAS Number: 3025787-83-8

Molecular Weight: 1155.21

Research Area: Cancer

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-176415-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-176415-0
• Package Unit: Get quote
• Quantity Unit: STK