Cytokeratin 14 (KRT14) (Squamous Cell Marker)(KRT14/2375), CF740 conjugate, 0.1mg/mL

Cytokeratin 14 (KRT14) (Squamous Cell Marker)(KRT14/2375), CF740 conjugate, 0.1mg/mL
SKU
BTMBNC742375-100
Packaging Unit
100 uL
Manufacturer
Biotium

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Description: Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal - Mus musculus (mouse), Bos taurus (bovine)

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Clone: KRT14/2375

Immunogen: Recombinant human KRT14 fragment (around aa351-472) (exact sequence is proprietary)

Antibody Reactivity: Cytokeratin 14

Entrez Gene ID: 3861

Z-Antibody Applications: Flow, intracellular (verified)/IHC, FFPE (verified)

Verified AB Applications: Flow (intracellular) (verified)/IHC (FFPE) (verified)
More Information
SKU BTMBNC742375-100
Manufacturer Biotium
Manufacturer SKU BNC742375-100
Package Unit 100 uL
Quantity Unit STK
Reactivity Human, Mouse (Murine), Rat (Rattus), Pig (Porcine)
Clonality Monoclonal
Application Flow Cytometry, Immunohistochemistry
Isotype IgG2a kappa
Host Mouse
Conjugate Conjugated, CF740
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