Cytokeratin 19 (KRT19) (Pancreatic Stem Cell Marker) (rKRT19/799), CF740 conjugate, 0.1mg/mL

Cytokeratin 19 (KRT19) (Pancreatic Stem Cell Marker) (rKRT19/799), CF740 conjugate, 0.1mg/mL
SKU
BTMBNC742304-500
Packaging Unit
500 uL
Manufacturer
Biotium

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Description: This MAb reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40 kDa. Its epitope maps between amino acid 312-335. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal - Mus musculus (mouse), Bos taurus (bovine)

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Clone: rKRT19/799

Immunogen: Recombinant full-length human KRT19 protein

Antibody Reactivity: Cytokeratin 19

Entrez Gene ID: 3880

Z-Antibody Applications: Flow, intracellular (verified)/IHC, FFPE (verified)/WB (verified)

Verified AB Applications: Flow (intracellular) (verified)/IHC (FFPE) (verified)/WB (verified)

Antibody Application Notes: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody/Does not react with rat or ferret/Immunohistology (formalin): 0.5-1 ug/mL for 30 minutes at RT/Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes/Western blotting 1-2 ug/mL/Optimal dilution for a specific application should be determined by user
More Information
SKU BTMBNC742304-500
Manufacturer Biotium
Manufacturer SKU BNC742304-500
Package Unit 500 uL
Quantity Unit STK
Reactivity Human
Clonality Recombinant
Application Western Blotting, Flow Cytometry, Immunohistochemistry
Isotype IgG1
Host Mouse
Conjugate Conjugated, CF740
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