Conjugation: FITC: Fluorescein Isothiocyanate
Description of Target: DNALI1 is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects. This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DNALI1
Key Reference: Combs,J., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (40), 14883-14888
Molecular Weight: 31kDa
Peptide Sequence: Synthetic peptide located within the following region:
MVTANKAHTGQGSCWVATLASAMIPPADSLLKYDTPVLVSRNTEKRSPKAProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: Axonemal dynein light intermediate polypeptide 1
Protein Size: 280
Purification: Affinity Purified
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