Dotinurad, CAS 1285572-51-1

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: (3,5-dichloro-4-hydroxyphenyl)(1,1-dioxido-3(2H)-benzothiazolyl)-methanone

Purity: ≥98%

Formula Markup: C14H9Cl2NO4S

Formula Weight: 358.2

CAS Number: 1285572-51-1

Notes: Dotinurad is a urate transporter 1 (URAT1) antagonist (IC50 = 0.0372 µM).{68815} It is selective for URAT1 over ATP-binding cassette subfamily G member 2 (ABCG2), organic anion transporter 1 (OAT1), and OAT3 (IC50s = 4.16, 4.08, and 1.32 µM, respectively). In vivo, dotinurad (30 mg/kg) decreases plasma levels of urate and increases urine levels of urate in Cebus monkeys. Formulations containing dotinurad have been used in the treatment of hyperuricemia and gout.

• SKU: CAY41014-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41014-5
• Package Unit: 5 mg
• Quantity Unit: STK