DPM-1001 (trihydrochloride)

Product Description: DPM-1001 trihydrochloride is a potent, specific, orally active and non-competitive inhibitor of protein-tyrosine phosphatase (PTP1B) with an IC50 of 100 nM. DPM-1001 trihydrochloride is an analog of the specific PTP1B inhibitor MSI-1436. DPM-1001 trihydrochloride has anti-diabetic property[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C35H60Cl3N3O3

References: [1]Krishnan N, et al. A potent, selective, and orally bioavailable inhibitor of the protein-tyrosine phosphatase PTP1B improves insulin and leptin signaling in animal models. J Biol Chem. 2018 Feb 2;293(5):1517-1525.

Molecular Weight: 677.23

Compound Purity: 98.48

Research Area: Metabolic Disease

Solubility: DMSO : 80 mg/mL (ultrasonic)/H2O : 33.33 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Phosphatase

• SKU: MEXHY-121515A-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-121515A-1
• Package Unit: 1 mg
• Quantity Unit: STK