Emodepside, CAS 155030-63-0

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: cyclo[(aR)-a-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl-(aR)-a-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl]

Purity: ≥98%

Formula Markup: C60H90N6O14

Formula Weight: 1119.4

CAS Number: 155030-63-0

Notes: Emodepside is a macrocyclic depsipeptide anthelmintic and semisynthetic derivative of the fungal metabolite and anthelmintic PF-1022A (Item No. 29700).{51888,51887} It inhibits locomotion in C. elegans (IC50 = 14 nM), an effect that can be reversed by knockout of the gene encoding the calcium-activated potassium channel SLO-1.{51888} Emodepside (10 mg/kg) decreases the survival of N. brasiliensis and S. ratti worms in infected rats and H. polygyrus worms in infected mice.{51887} Formulations containing emodepside in combination with praziquantel have been used as anthelmintics in cats and dogs.

• SKU: CAY41247-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41247-10
• Package Unit: 10 mg
• Quantity Unit: STK