Description: This antibody is a mixture of four different monoclonal antibodies. This antibody is specific to 60 kDa latent membrane protein (LMP-1) encoded by the BNLF1 gene of the EBV. Each clone reacts with different epitopes on the hydrophilic C-terminus of the cytoplasmic domain of LMP-1. This antibody stains strongly with EBV-positive lymphoblastoid cell lines and EBV infected B cell immunoblasts in infectious mononucleosis. EBV, also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Origin: Animal - Mus musculus (mouse), Bos taurus (bovine)
Conjugate: CF740
Concentration: 0.1 mg/mL
Storage buffer: PBS, 0.1% rBSA, 0.05% azide
Clone: CS2
Immunogen: Recombinant fusion protein containing the sequence of bacterial beta-galactosidase and the carboxyl half of EBV-encoded LMP
Antibody Reactivity: Epstein-Barr Virus
References: Note: References for this clone sold by other suppliers may be listed for expected applications.
- J Exp Med (1993) 177: 339-349. (IHC, frozen; WB; mix of clones CS1-4)
- J Clin Pathol (1995) 48:438-442. (IHC, FFPE; mix of clones CS1-4)
- EMBO J (1999)18:3064-3073. (IP; mix of clones CS1-4)
Entrez Gene ID: Not Applicable
Expected AB Applications: IHC (frozen) (published for clone)/IHC (FFPE) (published for clone)/IP (published for clone)/WB (published for clone)
Z-Antibody Applications: IHC, FFPE (published)/IHC, frozen (published)/IP (published)/WB (published)
Antibody Application Notes: ELISA: For coating, purchase antibody without BSA; Western blot 1-2 ug/mL; Optimal dilution for a specific application should be determined./Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
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