Exatecan-amide-bicyclo(1.1.1)pentan-1-ol, CAS 2866299-06-9

Product Description: Exatecan-amide-bicyclo[1.1.1]pentan-1-ol (Compound 79) is an exatecan (HY-13631) derivative that can be used as a payload in drug conjugates. Exatecan-amide-bicyclo[1.1.1]pentan-1-ol has significant inhibitory activity against a variety of tumor cell lines[1].

Applications: Cancer-programmed cell death

Formula: C30H28FN3O6

References: [1]VRLJIC M, et al. Exatecan derivatives and antibody-drug conjugates thereof. WO2022236136A1. 2022-11-10.

CAS Number: 2866299-06-9

Molecular Weight: 545.56

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Cytotoxin;Topoisomerase

• SKU: MEXHY-160597-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-160597-0
• Package Unit: Get quote
• Quantity Unit: STK