FGFR-IN-17

Product Description: FGFR-IN-17 (Compound 12l) is an orally active irreversible inhibitor of FGFR, which has a strong inhibitory effect on FGFR and its mutants. FGFR-IN-17 can inhibit the proliferation and migration, and induce apoptosis of non-small cell lung cancer cells. FGFR-IN-17 has anti-tumor activity[1].

Formula: C26H29Cl2N7O2

References: [1]Zhang J, et al. Discovery of Novel 2,4,5-Trisubstituted Pyrimidine Derivatives as Potent and Selective FGFR Inhibitors against Gatekeeper Mutants for the Treatment of NSCLC. J Med Chem. 2025 Mar 13;68(5):5907-5925.

Molecular Weight: 542.46

Research Area: Cancer

Target: Apoptosis;FGFR

• SKU: MEXHY-172251-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-172251-0
• Package Unit: Get quote
• Quantity Unit: STK