Product Description: fluoro-Dapagliflozin, a structural analog of Dapagliflozin, is a selective SGLT2 inhibitor with Ki values of 5.3 nM and 330 nM for SGLT2 and SGLT1, respectively. fluoro-Dapagliflozin blocks glucose transport and glucose-coupled currents[1].
Applications: Metabolism-sugar/lipid metabolism
Formula: C21H24ClFO5
References: [1]Charles S Hummel, et al. Structural selectivity of human SGLT inhibitors. Am J Physiol Cell Physiol. 2012 Jan 15;302(2):C373-82.
CAS Number: 1181681-43-5
Molecular Weight: 410.86
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: SGLT