GABA A Receptor Beta 3 Antibody, Clone N87/25: ATTO 390

Mouse Anti-Mouse GABA-A Receptor Beta 3 Monoclonal IgG1

Target: GABA A Receptor

Conjugate: ATTO 390

Product Type: Monoclonal

Clone Number: N87/25 (Formerly sold as S87-25)

Immunogen: Fusion protein amino acids 370-433 of mouse GABA-A-R-Beta 3

Swiss-Prot: P63080

Purification: Protein G Purified

Storage Buffer: 640.91mM DMSO, 136.36mM Ethanolamine, 9.09mM Sodium Bicarbonate in 90.9% PBS

Concentration: 1 mg/ml

Specificity: Detects ~55kDa. No cross-reactivity against GABA-A-R-Beta 2 or –Beta1.

Cellular Localization: Cell Membrane / Cell Junction / Synapse / Postsynaptic Cell Membrane

Scientific Background: The GABA-A receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (1). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (2).

References: 1. Bracamontes J.R. and Steinbach J.H. (2008) J Bio Chem. 283: 26128-26136.2. Macdonald R.L., Olsen R.W. (1993) Annu Rev Neurosci. 17: 569-602.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSMC-339D-A390
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SMC-339D-A390
• Package Unit: 100 µg
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Monoclonal
• Application: Immunofluorescence, Immunohistochemistry, Immunocytochemistry
• Isotype: IgG1
• Human Gene ID: 14402
• Host: Mouse
• Conjugate: Conjugated, Atto 390