Granzyme B Monoclonal Antibody

Background: Granzyme B is a serine protease, which mediates the apoptosis signaling pathway of cytotoxic T lymphocytes (CTL) and natural killer cells (NK). Granzyme B is synthesized in the form of inactive protease, stored in lysosomal granules and released during the degradation of effector cells. The results shows that granzyme B is expressed in peripheral T-cell lymphoma (PTCL) and NK cell lymphoma by immunohistochemistry. The expression of cytotoxic proteins may play an important role in the differentiation and classification of peripheral T-cell and NK cell lymphoma, such as granzyme B, because many tumors of this type do not have specific morphology and phenotype.

• SKU: ELSELAB5024-R-200
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELAB5024-R-200
• Package Unit: 200μL
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Host: Rabbit
• Conjugate: Unconjugated