Granzyme B (NK/T-Cell Lymphoma Marker)(GZMB/3056), 1mg/mL

Granzyme B (NK/T-Cell Lymphoma Marker)(GZMB/3056), 1mg/mL
SKU
BTMBNUM3056-50
Packaging Unit
50 µl
Manufacturer
Biotium

Availability: loading...
Price is loading...
Description: Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin's Disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product origin: Animal - Mus musculus (mouse)

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Clone: GZMB/3056

Immunogen: Recombinant fragment of human GZMB protein (around aa 73-187) (exact sequence is proprietary)

Antibody Reactivity: Granzyme B

Entrez Gene ID: 3002

Z-Antibody Applications: IHC, FFPE (verified)

Verified AB Applications: IHC (FFPE) (verified)
More Information
SKU BTMBNUM3056-50
Manufacturer Biotium
Manufacturer SKU BNUM3056-50
Package Unit 50 µl
Quantity Unit STK
Reactivity Human
Clonality Monoclonal
Application Immunohistochemistry
Isotype IgG kappa
Host Mouse
Conjugate Unconjugated
Product information (PDF) Download
MSDS (PDF) Download