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Encompassing Amino Acids: 2-419
Application: Useful for SDS-PAGE.
Background: HAT1 (histone acetyltransferase 1), also known as KAT1, regulates chromatin structure, mitochondrial function, and DNA repair. HAT1 acetylates newly synthesized histones in the cytoplasm and succinylates histones and non-histone proteins. The epigenetic regulation activity of this protein is involved in a wide variety of diseases such as cancer, inflammatory diseases, and viral infections. The development of inhibitors targeting HAT1 may open new therapeutic avenues in those disorders.
Description: Recombinant human full-length HAT1 (histone acetyltransferase 1), also known as KAT1, amino acids 2-419(end). This construct contains an N-terminal FLAG-tag. The recombinant protein was affinity purified.
Format: Aqueous buffer solution
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 80 ng/µl FLAG peptide, and 20% glycerol.
Genbank: NM_003642.4
Purity: ≥90%
Storage Stability: At least 6 months at -80°C.
Tags: FLAG
Uniprot: O14929
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
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