HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), CF740 conjugate, 0.1mg/mL

HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), CF740 conjugate, 0.1mg/mL
SKU
BTMBNC742452-100
Packaging Unit
100 uL
Manufacturer
Biotium

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Description: This antibody recognizes a protein of 185 kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal - Mus musculus (mouse), Bos taurus (bovine)

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Clone: ERBB2/2452

Immunogen: Recombinant human HER-2 protein fragment (around aa 311-462) (exact sequence is proprietary)

Antibody Reactivity: c-ErbB-2/CD340/HER-2/Neu

Entrez Gene ID: 2064

Z-Antibody Applications: Flow (verified)/IF (verified)/IHC, FFPE (verified)

Verified AB Applications: Flow (verified)/IF (verified)/IHC (FFPE) (verified)

Antibody Application Notes: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody/Immunohistology (formalin): 1-2 ug/mL for 30 minutes at RT/Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes/Optimal dilution for a specific application should be determined by user
More Information
SKU BTMBNC742452-100
Manufacturer Biotium
Manufacturer SKU BNC742452-100
Package Unit 100 uL
Quantity Unit STK
Reactivity Human
Clonality Monoclonal
Application Immunofluorescence, Flow Cytometry, Immunohistochemistry
Isotype IgG2a kappa
Host Mouse
Conjugate Conjugated, CF740
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