HIF-PHD-IN-4

Product Description: HIF-PHD-IN-4 (Compound 13) is an orally active PHD2 inhibitor with an IC50 of 100 nM. HIF-PHD-IN-4 can effectively enhance the mobilization of hematopoietic stem cells induced by G-CSF in mice at a dose of 2 mg/kg. HIF-PHD-IN-4 is suitable for research in the field of tumor therapy [1].

Applications: Cancer-programmed cell death

Formula: C20H21N5O3

References: [1]Wu M, et al. Discovery of Novel, Potent, Orally Bioavailable and Efficacious, Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors for Hematopoietic Stem Cell Mobilization. J Med Chem. 2025 Mar 6.

Molecular Weight: 379.41

Research Area: Cancer

Target: HIF/HIF Prolyl-Hydroxylase

• SKU: MEXHY-172257-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-172257-0
• Package Unit: Get quote
• Quantity Unit: STK