Calculated MW: 49
Specificity/Sensitivity: This antibody was raised against rat HRH3 intracellular domain.
Form: Liquid
Buffer (with preservative): PBS, 1% BSA, 0.05% Sodium Azide.
Concentration: 0.8 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a histamine H3 receptor that belongs to the superfamily of G-protein coupled receptors. This protein functions as a presynaptic autoreceptor on histamine neurons in the brain, and a presynaptic heteroreceptor in nonhistamine-containing neurons in both the central and peripheral nervous systems. It is deemed a great target for the development of therapeutics for numerous disorders, including obesity, epilepsy, and such cognitive diseases as attention deficit hyperactivity disorder and Alzheimer's disease. Several alternatively spliced transcript variants encoding different isoforms, with different brain expression patterns and signaling properties, have been described for this gene. [provided by RefSeq, Jul 2012]
Uniprot ID: Q9QYN8
Antigen Species: Rat
Immunogen: Peptide (C)RTRLRLDGGREAGPE, corresponding to amino acids 228-242 of rat HRH3 (Q9QYN8). 3rd intracellular loop.
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: histamine receptor H3
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