HMB-45 Monoclonal Antibody

Background: HMB45 is a melanoma-associated antigen that is mainly expressed in immature melanocytes. It was also expressed in activated and neoplastic melanocytes and other neural crest-derived tumors. It was also expressed in normal breast epithelium, some normal sweat glands, sweat gland-derived tumors and angiomyolipoma, and occasionally in carcinoma. "It is more specific than S-100 or NKl/C3 for the diagnosis of malignant melanoma, but the sensitivity is less than 90%, especially in metastatic melanoma."

• SKU: ELSELAB6942-M-200
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELAB6942-M-200
• Package Unit: 200μL
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Host: Mouse
• Conjugate: Unconjugated