HOI-07, CAS 1451013-67-4

Product Description: HOI-07 is a selective Aurora B kinase inhibitor. HOI-07 blocks phosphorylation of histone H3 on Ser10 inlung cancer cells. HOI-07 induces cell-cycle arrest, and apoptosis. HOI-07 has antitumor activity, and suppresses the tumor growth of A549, 143B and KHOS xenografts[1][2].

Applications: Cancer-Kinase/protease

Formula: C19H13NO4

References: [1]Xie H, et al. Identification of an Aurora kinase inhibitor specific for the Aurora B isoform. Cancer Res. 2013 Jan 15;73(2):716-24./[2]Zhao Z, et al. Aurora B kinase as a novel molecular target for inhibition the growth of osteosarcoma. Mol Carcinog. 2019 Jun;58(6):1056-1067.

CAS Number: 1451013-67-4

Molecular Weight: 319.31

Research Area: Cancer

Target: Apoptosis;Aurora Kinase

• SKU: MEXHY-125158-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-125158-0
• Package Unit: Get quote
• Quantity Unit: STK