Clone Name: 25K2
Application Note: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 16
Specificity/Sensitivity: This antibody is able to detect native and recombinant human IL-13.
Form: Liquid
Buffer (with preservative): PBS, 0.02% Sodium azide.
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
Uniprot ID: P35225
Antigen Species: Human
Immunogen: Recombinant human IL-13
Purification: Protein G purified
Conjugation: Unconjugated
Full Name: interleukin 13
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