IN 1130, CAS 868612-83-3

Shelf life (days): 1460

Info: An ALK5 inhibitor (IC50 = 5.3 nM); selective for ALK5 over a panel of 27 other kinases at 5 µM; decreases renal fibrogenesis, inflammatory cell infiltration, and tubular atrophy in a mouse model of unilateral ureteral obstruction at 10 mg/kg per day; reduces kidney levels of TGF-β1, α-SMA, hydroxyproline, and fibronectin in the same model; decreases tunica plaque area, increases elastin fiber numbers, and reverses penile curvature in a rat model of Peyronie's disease induced by TGF-β1 overexpression at 5 mg/kg per day

Formulation: A solid

Formal Name: 3-[[5-(6-methyl-2-pyridinyl)-4-(6-quinoxalinyl)-1H-imidazol-2-yl]methyl]-benzamide

Purity: ≥98%

Formula Markup: C25H20N6O

Formula Weight: 420.476

CAS Number: 868612-83-3

• SKU: CAY43285-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 43285-25
• Package Unit: 25 mg
• Quantity Unit: STK