ISRIB, CAS 548470-11-7

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N,N'-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)-acetamide

Purity: ≥95%

Formula Markup: C22H24Cl2N2O4

Formula Weight: 451.3

CAS Number: 548470-11-7

Notes: A mixture of cis-IRIB and trans-ISRIB; trans-ISRIB decreases ATF4-induced increases in gene transcription more effectively than cis-ISRIB in a reporter assay using HEK293T cells (IC50s = 5 and 600 nM, respectively); trans-ISRIB decreases the latency to escape in the Morris water maze and increases the length of freezing time induced by contextual fear conditioning in mice

• SKU: CAY41879-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41879-5
• Package Unit: 5 mg
• Quantity Unit: STK