Clone: HM beta 1-1
Specificity: Recognizes the murine integrin beta 1 subunit (CD29), a 110KD cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. CD29 forms non-covalent bonds with the integrin alpha subunits, including CD51 and CD49a-f, to form heterodimers. The ligands for these heterodimers include collagen, fibronectin, laminin and vascular adhesion molecule-1. In the immune system beta 1 integrins play an important role in cell adhesion, migration, activation and differentiation. Clone HM beta 1.1 is reported to inhibit beta 1 integrin mediated adhesion. XXX recommend the use of MCA2298EL for this purpose.
Antibody Modification: FITC
Presentation: PBS, 0.09% Sodium Azide, 1% BSA
Immunogen: Purified mouse VLA-4 antigen.
Gene: ITGB1 / Integrin Beta 1 / CD29
Description: CD29 antibody LS-C44636 is an FITC-conjugated hamster monoclonal antibody to mouse CD29 (ITGB1 / Integrin Beta 1). Validated for Flow.
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Synonyms: ITGB1, CD29, CD29 antigen, Integrin beta-1, MDF2, MSK12, Integrin VLA-4 beta subunit, VLA-BETA, VLAB, Beta 1 integrin, FNRB, GPIIA, Integrin Beta 1, VLA-4 subunit beta
Recommended Storage: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light.
Concentration: 0.1 mg/ml
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