Shelf life (days): 1460.0
Formulation: A solid
Formal Name: [5-(4,6-dimethyl-2-pyrimidinyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl][2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl]-methanone
Purity: ≥98%
Formula Markup: C21H22FN7O
Formula Weight: 407.5
CAS Number: 1293281-49-8
Notes: An orexin receptor 2 antagonist (Ki = 10 nM); selective for OX2R over OX1R (Ki = 794 nM) and a panel of 50 receptors, ion channels, and transporters at 1 µM; reduces the latency to NREM sleep onset and increases the duration of NREM sleep in rats at 3, 10, and 30 mg/kg