KMH-233, CAS 1941174-13-5

Product Description: KMH-233, a potent, reversible and selective inhibitor of l-type amino acid transporter LAT1/SLC7A5, inhibits the uptake of LAT1 substrate, l-leucin (IC50=18 μM) as well as cell growth. KMH-233 significantly potentiates the efficacy of Bestatin and Cisplatin even at low concentrations (25 μM)[1].

Applications: Cancer-programmed cell death

Formula: C32H25N7O5

References: [1]Huttunen KM, et al. A Selective and Slowly Reversible Inhibitor of l-Type Amino Acid Transporter 1 (LAT1) Potentiates Antiproliferative Drug Efficacy in Cancer Cells. J Med Chem. 2016;59(12):5740-5751.

CAS Number: 1941174-13-5

Molecular Weight: 587.58

Compound Purity: 99.75

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Amino acid Transporter

• SKU: MEXHY-120139-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-120139-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK