Ksp-Cadherin / CDH16 (Renal Cell Marker)(CDH16/2448), CF740 conjugate, 0.1mg/mL

Ksp-Cadherin / CDH16 (Renal Cell Marker)(CDH16/2448), CF740 conjugate, 0.1mg/mL
SKU
BTMBNC742448-100
Packaging Unit
100 uL
Manufacturer
Biotium

Availability: loading...
Price is loading...
Description: This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal - Mus musculus (mouse), Bos taurus (bovine)

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Clone: CDH16/2448

Immunogen: Recombinant fragment (around aa 371-507) of human CDH16 protein (exact sequence is proprietary)

Antibody Reactivity: CDH16/Ksp-Cadherin

Entrez Gene ID: 1014

Z-Antibody Applications: IHC, FFPE (verified)

Verified AB Applications: IHC (FFPE) (verified)
More Information
SKU BTMBNC742448-100
Manufacturer Biotium
Manufacturer SKU BNC742448-100
Package Unit 100 uL
Quantity Unit STK
Reactivity Human
Clonality Monoclonal
Application Immunohistochemistry
Isotype IgG2b kappa
Host Mouse
Conjugate Conjugated, CF740
Product information (PDF) Download
MSDS (PDF) Download