Lupartumab Amadotin, CAS 1640972-00-4

Product Description: Lupartumab Amadotin (BAY 1129980) is an antibody–drug conjugate (ADC) consisting of a fully human C4.4A (LYPD3)-targeting mAb (BAY 1135626) (HY-147281) conjugated to a novel, highly potent derivative of the microtubule-disrupting cytotoxic drug auristatin via a noncleavable alkyl hydrazide linker. Lupartumab Amadotin can be used for the research of non-small cell lung cancer[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Willuda J, et al. Preclinical Antitumor Efficacy of BAY 1129980-a Novel Auristatin-Based Anti-C4.4A (LYPD3) Antibody-Drug Conjugate for the Treatment of Non-Small Cell Lung Cancer. Mol Cancer Ther. 2017 May;16(5):893-904.

CAS Number: 1640972-00-4

Molecular Weight: N/A

Research Area: Cancer

Solubility: H2O

Target: Antibody-Drug Conjugates (ADCs)

• SKU: MEXHY-P99719-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99719-5
• Package Unit: 5 mg
• Quantity Unit: STK