Mal((3S,3aR,6S,6aR)-Hexahydrofuro(3,2-b)furan-3,6-diamine-PEG12)-β-Glu-PAB

Product Description: Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB is an interchain cysteines to a Maleimide-reactive, β-glucuronidase-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as AZD0516 (HY-173639)[1].

Applications: Cancer-programmed cell death

Formula: C63H98N6O31

References: [1]Darlene Monlish, et al. Abstract 1158: Preclinical characterization of AZD0516, a novel STEAP2 antibody-drug conjugate (ADC) for the treatment of prostate cancer. Cancer Res (2025) 85 (8_Supplement_1): 1158.

Molecular Weight: 1435.47

Research Area: Cancer

Target: ADC Linker

• SKU: MEXHY-173635-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173635-0
• Package Unit: Get quote
• Quantity Unit: STK