Product Description: Mal-PEG8-Val-Ala-PAB-Exatecan (Compound 9b) is an antibody-drug conjugate linker (ADC linker) that binds to Nectin-4 polypeptides conjugated to chemotherapeutic agents. Mal-PEG8-Val-Ala-PAB-Exatecan can be used for cancer research[1].
Applications: Cancer-programmed cell death
Formula: C66H85FN8O20
References: [1]Manel KRAIEM. Treatment of cancer. WO2021151984A1.
CAS Number: 2679821-39-5
Molecular Weight: 1329.42
Compound Purity: 99.48
Research Area: Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Drug-Linker Conjugates for ADC;Topoisomerase