MFN2 agonist-1, CAS 2230047-87-5

Product Description: MFN2 agonist-1 (B-A/l) potently stimulates mitochondrial fusion in mitofusin 2 (MFN2)-deficient cells. MFN2 agonist-1 reverses mitochondrial “clumping” (formation of static mitochondrial aggregates) and restores mitochondrial motility in cultured mouse neurons expressing the CMT2A mutant MFN2 T105M.

Formula: C21H29N5OS

References: [1]Rocha AG, et al. MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A. Science. 2018 Apr 20;360(6386):336-341.

CAS Number: 2230047-87-5

Molecular Weight: 399.55

Compound Purity: 99.28

Research Area: Others

Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Mitochondrial Metabolism

• SKU: MEXHY-123985-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-123985-100
• Package Unit: 100 mg
• Quantity Unit: STK