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Biological Activity: Milrinone inhibits PDE3A and PDE3B with IC50 values of 0.45 µM and 1.0µM, respectively.
CAS Number: 78415-72-2
Description: Milrinone, also known as WIN 47203 and Primacor®, is an inhibitor of PDE3. It is less effective against other PDE isoforms. Milrinone has positive inotropic and vasodilatory effects in vivo.
Format: A crystalline solid
Purity: ≥98%
Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Biosafety Level: Not applicable (BSL-1)
References: 1. Sudo, T., et al., Biochem Pharmacol. 2000;59:347-56.
2. Lakshminrusimha, S., et al., Pediatr. Crit. Care Med. 2009;10(1):106-12.
3. Simkova, V., et al., Crit. Care. 2007;11(3):139.
4. Maskin, C.S., et al., Circ. J. 1983;67:1065-70.
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