Stock Concentration: 1000 µg/ml
Conjugate Type: Unconjugated
Buffer: Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide, BSA-Free
Shelf Life: 1 year from date of receipt
Protein Ref Seq ID: NP_563578.2
Uniprot ID: P08575
Background: CD45 is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. CD45 acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45 recruits and dephosphorylates SKAP1 and FYN [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P08575].
Immunogen: Cultured T-cells from an IL-2-dependent T-cell line (CA1)
Clone Number: UCHL-1
Physical State: Liquid
Formulation: BSA-Free
Antibody Platform: COMET™,PhenoImager™ HT
Purity: Purified
Antibody Registry ID: AB_2891799
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