Clone Number: BP53.12
Immunogen: Human recombinant p53 protein
Concentration: n/a
Storage buffer: Contains 0.09% sodium azide
Additional info: The gene coding for p53 oncoprotein is located on chromosome 17p. Allele loss at this chromosome site has frequently been seen in many tumours including lung, colon, breast and brain. Expression of p53 oncoprotein was not detected in normal mucosa, whereas mutation results in a detectable expression of the p53 protein. It is therefore suggested that immunocytochemical detection of p53 protein is an indication for malignancy.Positive control: Breast carcinoma.
Applications: IHC-fr, IHC-P (1:5-1:10), IF