Description: Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Origin: Animal - Mus musculus (mouse), Bos taurus (bovine)
Conjugate: CF740
Concentration: 0.1 mg/mL
Storage buffer: PBS, 0.1% rBSA, 0.05% azide
Clone: NAPSA/1238
Immunogen: Recombinant fragment of human Napsin-A protein
Antibody Reactivity: Napsin-A
Entrez Gene ID: 9476
Z-Antibody Applications: IHC, FFPE (verified)/WB (verified)
Verified AB Applications: IHC (FFPE) (verified)/WB (verified)
Antibody Application Notes: Immunohistology formalin-fixed 1-2 ug/mL/Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes/Western blotting 1-2 ug/mL/Flow Cytometry 0.5-1 ug/million cells/0.1 mL/Immunofluorescence 1-2 ug/mL/Optimal dilution for a specific application should be determined by user
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