NBC19, CAS 2068818-75-5

Product Description: NBC19 is an NLRP3 inflammasome inhibitor with an IC50 of 60 nM in differentiated THP1 cells. NBC19 inhibits nigericin- and ATP-induced IL-1β release with IC50s of 80 nM and 850 nM, respectively[1].

Applications: COVID-19-immunoregulation

Formula: C24H26BCl3N2O2

References: [1]Redondo-Castro E, et al. Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses. Sci Rep. 2018 Apr 4;8(1):5667.

CAS Number: 2068818-75-5

Molecular Weight: 491.65

Compound Purity: 99.22

Research Area: Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: NOD-like Receptor (NLR)

• SKU: MEXHY-120048-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-120048-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK