Description: This kit contains four nitric oxide synthase (NOS) inhibitors: 7-NI, L-NMMA, L-NIL, and L-NIO. 7-NI is a selective inhibitor for the brain nitric oxide synthase (NOS).
Yellow orange solid soluble in DMSO
Store desiccated at 4°C
C7H5N3O2
MW: 163.1
[2942-42-9]
L-NMMA (NG-Methyl-L-arginine, acetate salt) competitively inhibits nitric oxide synthase in a wide range of cells.
White solid soluble in water
Store desiccated at 4°C
C9H20N4O4
MW: 248.3
[53308-83-1]
L-NIL (N6-(1-Iminoethyl)-lysine, hydrochloride) is a potent and selective inhibitor of nitric oxide synthase that exhibits about 28-fold greater selectivity for inducible nitric oxide synthase (IC50 = 3.3 uM) than for the rat brain constitutive enzyme (IC50 = 92 uM). It exhibits about 10-fold greater inhibitory potency than NG-monomethyl-L-arginine in inhibiting γ-interferon-induced NO2€“ production (IC50 = 460 nM).
White solid soluble in water
Store at 4°C
C8H19Cl2N3O2
MW: 260.2
[150403-89-7]
L-NIO (N5-(1-Iminoethyl)-L-ornithine, dihydrochloride) is a potent, irreversible inhibitor of neutrophil nitric oxide synthase.