NR2B-selective NMDA receptor antagonist 1, CAS 457897-92-6

Product Description: NR2B-selective NMDA receptor antagonist 1 (compound 29) is a potent antagonist of NR1/NR2B receptors, with IC50s of 0.05 μM, 0.73 μM, 2.4 μM to NR1/NR2B NMDA receptor, hERG, α1-AdR, respectivity. NR2B-selective NMDA receptor antagonist 1 exhibites efficient permeability across the blood–brain barrier[1].

Applications: Neuroscience-Neurodegeneration

Formula: C18H22Cl2N2O4S

References: [1]Yesim A Tahirovic, et al. Enantiomeric Propanolamines as selective N-Methyl-D-aspartate 2B Receptor Antagonists. J Med Chem. 2008 Sep 25;51(18):5506-21.

CAS Number: 457897-92-6

Molecular Weight: 433.35

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: iGluR;Potassium Channel

• SKU: MEXHY-126123-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-126123-1
• Package Unit: 1 mg
• Quantity Unit: STK