p40 (deltaNp63) (Squamous, Basal & Myoepithelial Cell Marker), CF740 conjugate, 0.1mg/mL

p40 (deltaNp63) (Squamous, Basal & Myoepithelial Cell Marker), CF740 conjugate, 0.1mg/mL
SKU
BTMBNC742314-100
Packaging Unit
100 uL
Manufacturer
Biotium

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Description: p40 (p63 delta) is a marker recently determined to be highly specific for squamous basal cells in the immunohistochemistry (IHC) application. The current more routinely recommended marker, p63, appears to have less specificity compared to p40, especially on squamous cell tumors. The ability to differentiate between lung adenocarcinoma vs. squamous cell carcinoma is difficult and has bearing on the different therapeutic avenues for each subtype treatment. p63 antibody's ability to distinguish between the tumor types appears to be inferior when compared to p40. The ability to utilize an antibody probe for p40 as a squamous cell marker bolsters its use for future sub-classification of lung cancers, especially by immunohistochemical techniques. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal - Oryctolagus cuniculus (domestic rabbit), Bos taurus (bovine)

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Immunogen: Recombinant human p40 protein fragment

Antibody Reactivity: p40

Entrez Gene ID: 8626

Z-Antibody Applications: IHC, FFPE (verified)

Verified AB Applications: IHC (FFPE) (verified)
More Information
SKU BTMBNC742314-100
Manufacturer Biotium
Manufacturer SKU BNC742314-100
Package Unit 100 uL
Quantity Unit STK
Reactivity Human
Clonality Polyclonal
Application Immunohistochemistry
Isotype IgG
Host Rabbit
Conjugate Conjugated, CF740
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