Pazopanib (Hydrochloride) (Standard), CAS 635702-64-6

Pazopanib (Hydrochloride) (Standard), CAS 635702-64-6
SKU
MEXHY-12009R-5
Packaging Unit
5 mg
Manufacturer
MedChemExpress

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Product Description: Pazopanib (Hydrochloride) (Standard) is the analytical standard of Pazopanib (Hydrochloride). This product is intended for research and analytical applications. Pazopanib Hydrochloride (GW786034 Hydrochloride) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with an IC50 of 10, 30, 47, 84, 74, 140 and 146 nM, respectively.

Formula: C21H24ClN7O2S

References: [1]Harris PA, et al. Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor. J Med Chem. 2008, 51(15), 4632-4640./[2]Thakur A, et al. Pazopanib, a multitargeted tyrosine kinase inhibitor, reduces diabetic retinal vascular leukostasis and leakage. Microvasc Res. 2011 Nov;82(3):346-50.

CAS Number: 635702-64-6

Molecular Weight: 473.98

Research Area: Cancer

Target: Autophagy;c-Fms;c-Kit;FGFR;PDGFR;Reference Standards;VEGFR
More Information
SKU MEXHY-12009R-5
Manufacturer MedChemExpress
Manufacturer SKU HY-12009R-5
Package Unit 5 mg
Quantity Unit STK
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