PLD1 Inhibitor, CAS 1001957-60-3

Shelf life (days): 1460

Info: An inhibitor of PLD1; inhibits PLD activity in PLD1-overexpressing A549 cells (IC50 = 1.97 µM); reduces the viability of A549 and HCT116 cell (IC50s = 18 and 29 µM, respectively); inhibits the proliferation, migration, and invasion of A549 cells and induces apoptosis in the same cells; reduces tumor growth, induces intratumoral apoptosis, and decreases Ras, CD47, CD24, and PD-L1 levels in a murine Lewis lung carcinoma model at 10 mg/kg every other day

Formulation: A solid

Formal Name: N-[3,5-bis(trifluoromethyl)phenyl]-1H-indole-3-propanamide

Purity: ≥98%

Formula Markup: C19H14F6N2O

Formula Weight: 400.324419

CAS Number: 1001957-60-3

• SKU: CAY42918-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42918-1
• Package Unit: 1 mg
• Quantity Unit: STK