PND-1186, CAS 1061353-68-1

PND-1186, CAS 1061353-68-1
SKU
BPS82815-1
Packaging Unit
10 mM * 1 mL DMSO
Manufacturer
BPS Bioscience

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Background: FAK (Focal Adhesion Kinase; PTK2) is a protein kinase involving cell adhesion and migration. FAK plays an important role in many cancers including pancreatic tumors. In addition, recent studies showed FAK inhibitor enables an anti-tumor immune response, resulting in tumor destruction in a mouse model.

CAS Number: 1061353-68-1

Description: PND-1186 (VS-4718) is a potent, highly-specific and reversible inhibitor of FAK with an IC50 of 1.5 nM. PND-1186 selectively promotes tumor cell apoptosis.1

Format: Aqueous solution

Purity: ≥90%

Storage Stability: Powder, store up to 3 years at -20°C or  up to 2 years at 4°C. In solvent, store up to 2 years at -80°C or  up to 1 year at -20°C

Target: FAK

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1. Tanjoni I, et al., 2010 Cancer Biol Ther.  9(10): 764-77.
More Information
SKU BPS82815-1
Manufacturer BPS Bioscience
Manufacturer SKU 82815-1
Package Unit 10 mM * 1 mL DMSO
Quantity Unit STK
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