Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) (PODXL/2185), CF740 conjugate, 0.1mg/mL

Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) (PODXL/2185), CF740 conjugate, 0.1mg/mL
SKU
BTMBNC742185-100
Packaging Unit
100 uL
Manufacturer
Biotium

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Description: Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is highly expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal - Mus musculus (mouse), Bos taurus (bovine)

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Clone: PODXL/2185

Immunogen: Recombinant fragment of human Podocalyxin (around aa 310-447) (exact sequence is proprietary)

Antibody Reactivity: Podocalyxin

Entrez Gene ID: 5420

Z-Antibody Applications: IHC, FFPE (verified)

Verified AB Applications: IHC (FFPE) (verified)

Antibody Application Notes: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody/Immunohistology (formalin): 1-2 ug/mL for 30 minutes at RT/Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes/Optimal dilution for a specific application should be determined by user
More Information
SKU BTMBNC742185-100
Manufacturer Biotium
Manufacturer SKU BNC742185-100
Package Unit 100 uL
Quantity Unit STK
Reactivity Human
Clonality Monoclonal
Application Immunohistochemistry
Isotype IgG1
Host Mouse
Conjugate Conjugated, CF740
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