Product Description: PT150 (ORG-34517) is a competitive and orally active glucocorticoid receptor antagonist. PT150 shows neuroprotective effects. PT150 has the potential for the research of Parkinson’s disease[1][2].
Formula: C28H30O4
References: [1]Morice C, et al. A randomized trial of safety and pharmacodynamic interactions between a selective glucocorticoid receptor antagonist, PT150, and ethanol in healthy volunteers. Sci Rep. 2021 May 10;11(1):9876./[2]Latham AS, et al. Neuroprotective Efficacy of the Glucocorticoid Receptor Modulator PT150 in the Rotenone Mouse Model of Parkinson's Disease. bioRxiv [Preprint]. 2024 Apr 15:2024.04.12.589261.
CAS Number: 189035-07-2
Molecular Weight: 430.54
Research Area: Neurological Disease
Target: Glucocorticoid Receptor