Rabbit anti-COP1/RFWD2 Antibody, Affinity Purified

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein ID: NP_071902.2

Uniprot ID: Q8NHY2

Background: Constitutive photomorphogenic protein 1 (COP1) has been characterized in plants as a RING-finger-containing protein that functions to repress plant photomorphogenesis. In mammals, COP1 has been identified as an E3 ubiquitin ligase that negatively regulates p53 protein levels in unstressed cells. In response to DNA damage COP1 is phosphorylated by the ataxia telangiectasia mutated (ATM) protein kinase and is rapidly degraded releasing p53 to exert its tumor suppressor activities.

Immunogen: Between 100 and 150

• SKU: BEYA300-895A
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A300-895A
• Package Unit: 100 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Polyclonal
• Application: Immunoprecipitation
• Isotype: Whole IgG
• Human Gene ID: 64326
• Host: Rabbit
• Conjugate: Unconjugated