Rabbit anti-ThPOK Recombinant Monoclonal Antibody (BLR191J) - BSA-Free

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free

Shelf Life: 1 year from date of receipt

Protein Ref Seq ID: NP_056956.2

Uniprot ID: O15156

Background: ZBTB7B is a transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. ZBTB7B is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is also a transcriptional repressor of the collagen COL1A1 and COL1A2 genes and may also function as a repressor of fibronectin and possibly other extracellular matrix genes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O15156].

Immunogen: Between 250 and 300

Clone Number: BLR191J

Physical State: Liquid

Formulation: BSA-Free

Purity: Purified

• SKU: BEYA700-191CF
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A700-191CF
• Package Unit: 100 µg (BSA-Free)
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine)
• Clonality: Recombinant
• Application: Immunoprecipitation, Western Blotting, Flow Cytometry, Immunohistochemistry, Immunocytochemistry
• Isotype: IgG
• Human Gene ID: 51043
• Host: Rabbit
• Conjugate: Unconjugated